BMS-582949
BMS-582949 (PS540446) is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13nM,inhibiting both p38 kinase activity and activation of p38.
| Trivial name | PS540446 |
| Catalog Number | S8124 |
| Molecular Formula | C22H26N6O2 |
| CAS# | 623152-17-0 |
| Inchi | InChI=1S/C22H26N6O2/c1-4-9-23-22(30)17-11-28-19(14(17)3)20(24-12-25-28)27-18-10-15(6-5-13(18)2)21(29)26-16-7-8-16/h5-6,10-12,16H,4,7-9H2,1-3H3,(H,23,30)(H,26,29)(H,24,25,27) |
| Inchi Key | GDTQLZHHDRRBEB-UHFFFAOYSA-N |
| SMILES | CCCNC(=O)C1=CN2C(=C1C)C(=NC=N2)NC3=C(C=CC(=C3)C(=O)NC4CC4)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/bms-582949.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bms-582949-chemical-structure-s8124.gif |