Ki20227
Ki20227 is an orally active and highly selective inhibitor of c-Fms tyrosine kinase(CSF1R) with IC50 of 2 nM, 12 nM, 451 nM and 217 nM for c-Fms, vascular endothelial growth factor receptor-2 (KDR/VEGFR-2), stem cell factor receptor (c-Kit), and platelet-derived growth factor receptor beta (PDGFRβ), respectively.
| Catalog Number | S7688 |
| Molecular Formula | C24H24N4O5S |
| CAS# | 623142-96-1 |
| SMILES | CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/ki20227.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s7688-ki20227-chemical-structure.gif |