Oxaliplatin
Oxaliplatin is a DNA alkylating agent that activates autophagy. Oxaliplatin inhibits DNA synthesis by conforming DNA adducts in RT4, TCCSUP, A2780, HT-29, U-373MG, U-87MG, SK-MEL-2, and HT-144 cells.Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
| Trivial name | L-OHP,NSC 266046 |
| Catalog Number | S1224 |
| Molecular Formula | C25H34CaN3O9PS |
| CAS# | 61825-94-3 |
| Inchi | InChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,3 2);/q;+2/p-2/t21-,23-,24+;/m0./s1 |
| Inchi Key | PMDQGYMGQKTCSX-HQROKSDRSA-L |
| SMILES | CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Eloxatin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Oxaliplatin-Eloxatin-chemical-structure-S1224.gif |