Tasimelteon
Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).
| Trivial name | BMS 214778, VEC 162 |
| Catalog Number | S4281 |
| Molecular Formula | C15H19NO2 |
| CAS# | 609799-22-6 |
| Inchi | InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1 |
| Inchi Key | PTOIAAWZLUQTIO-GXFFZTMASA-N |
| SMILES | CCC(=O)NCC1CC1C2=C3CCOC3=CC=C2 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/tasimelteon.html |
| Additional Information | https://file.selleck.cn/downloads/struct/tasimelteon-chemical-structure-s4281.gif |