Ebselen
An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC50 of 5.17 µM.
| Catalog Number | ABA-012 |
| Alternative Name(s) | 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one |
| CAS# | 60940-34-3 |
| Inchi | InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H |
| Inchi Key | DYEFUKCXAQOFHX-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/ebselen-item-1379.html |