Berbamine dihydrochloride
Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
| Trivial name | BA, BBM |
| Catalog Number | S3609 |
| Molecular Formula | C15H9BrN2O6S2 |
| CAS# | 6078-17-7 |
| Inchi | InChI=1S/C15H9BrN2O6S2/c16-5-1-2-7-6(3-5)10(12(21)17-7)11-13(22)18(15(25)26-11)8(14(23)24)4-9(19)20/h1-3,8H,4H2,(H,17,21)(H,19,20)(H,23,24)/b11-10- |
| Inchi Key | QGNRETMYLHRUBB-KHPPLWFESA-N |
| SMILES | C1=CC2=NC(=O)C(=C2C=C1Br)C3=C(N(C(=S)S3)C(CC(=O)O)C(=O)O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/berbamine-dihydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/berbamine-dihydrochloride-chemical-structure-s3609.gif |
