Berbamine dihydrochloride
Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
Trivial name | BA, BBM |
Catalog Number | S3609 |
Molecular Formula | C37H40N2O6.2HCl |
CAS# | 6078-17-7 |
Inchi | InChI=1S/C37H40N2O6.2ClH/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33;;/h6-11,18-21,28-29,40H,12- 17H2,1-5H3;2*1H/t28-,29+;;/m0../s1 |
Inchi Key | USRXDYNDPPUBSG-KKXMJGKMSA-N |
SMILES | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC.Cl |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/berbamine-dihydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/berbamine-dihydrochloride-chemical-structure-s3609.gif |