TWS119
TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology. GSK-3β inhibition triggers autophagy.
| Trivial name | N/A |
| Catalog Number | S1590 |
| Molecular Formula | C18H14N4O2 |
| CAS# | 601514-19-6 |
| Inchi | InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22) |
| Inchi Key | VPVLEBIVXZSOMQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/TWS119.html |
| Additional Information | https://file.selleck.cn/downloads/struct/TWS119-chemical-structure-S1590.gif |