GSK-3β Inhibitor, TWS119
A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (IC50 = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.
| Catalog Number | ABS-021 |
| Alternative Name(s) | 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol |
| CAS# | 601514-19-6 |
| Inchi | InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22) |
| Inchi Key | VPVLEBIVXZSOMQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/gsk-3-inhibitor-tws119-item-1487.html |