Sulfasalazine
Sulfasalazine is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-κB), TGF-β and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy.
Trivial name | NSC 667219, Sulphasalazine |
Catalog Number | S1576 |
Molecular Formula | C18H14N4O5S |
CAS# | 599-79-1 |
Inchi | InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+ |
Inchi Key | NCEXYHBECQHGNR-QZQOTICOSA-N |
SMILES | C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Sulfasalazine(Azulfidine).html |
Additional Information | https://file.selleck.cn/downloads/struct/Sulfasalazine-Azulfidine-chemical-structure-S1576.gif |