Piperlonguminine
Piperlonguminine is a known alkaloid amide from peppers, including Piper divaricatum. Acts as a potent anticancer agent. Displays inhibitory effect on alpha-melanocyte-stimulating hormone (alpha-MSH)-induced melanogenesis in melanoma B16 cells (IC50= 9.6 µM). The mode of action is through the inhibition of alpha-MSH-induced tyrosinase synthesis.
| Catalog Number | ABA-035 |
| Alternative Name(s) | (2E, 4E)-5-(Benzo[d][1,3]-dioxol-5-yl)-N-isobutylpenta-2,4-dienamide |
| CAS# | 5950-12-9 |
| Inchi | InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+ |
| Inchi Key | WHAAPCGHVWVUEX-GGWOSOGESA-N |
| SMILES | CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/piperlonguminine-item-1402.html |