α-Azidothymidine | MedChemExpress (MCE)
α-Azidothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. α-Azidothymidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Trivial name | α-Azidothymidine |
Catalog Number | HY-154253 |
Research Area | Cancer |
CAS# | 59090-48-1 |
Purity | ≥98.00% |
SMILES | O=C(C(CN=[N+]=[N-])=CN1[C@H]2C[C@H](O)[C@@H](CO)O2)NC1=O |
PubChem Chemical Structure ID | 168265735 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/α-azidothymidine.html |