Methotrexate
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
| Trivial name | NCI-C04671, Amethopterin, CL14377, WR19039 |
| Catalog Number | S1210 |
| Molecular Formula | C19H21IN2O |
| CAS# | 59-05-2 |
| Inchi | InChI=1S/C19H21IN2O/c20-17-8-6-16(7-9-17)19(23)21-18-10-12-22(13-11-18)14-15-4-2-1-3-5-15/h1-9,18H,10-14H2,(H,21,23) |
| Inchi Key | HELCSESNNDZLFM-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1NC(=O)C2=CC=C(C=C2)I)CC3=CC=CC=C3 |
| Size | 500mg |
| Supplier Page | http://www.selleckchem.com/products/Abitrexate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Abitrexate-Methotrexate-chemical-structure-S1210.gif |