Methotrexate

Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.

Price Not Available 10mM/1mL Methotrexate Supplier Page
Trivial name NCI-C04671, Amethopterin, CL14377, WR19039
Catalog Number S1210
Molecular Formula C20H22N8O5
CAS# 59-05-2
Inchi InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
Inchi Key FBOZXECLQNJBKD-ZDUSSCGKSA-N
SMILES CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/Abitrexate.html
Additional Information https://file.selleck.cn/downloads/struct/Abitrexate-Methotrexate-chemical-structure-S1210.gif