Methotrexate
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
| Trivial name | NCI-C04671, Amethopterin, CL14377, WR19039 |
| Catalog Number | S1210 |
| Molecular Formula | C12H10O4 |
| CAS# | 59-05-2 |
| Inchi | InChI=1S/C12H10O4/c1-15-11-9(13)7-5-3-4-6-8(7)10(14)12(11)16-2/h3-6H,1-2H3 |
| Inchi Key | ZEGDFCCYTFPECB-UHFFFAOYSA-N |
| SMILES | COC1=C(C(=O)C2=CC=CC=C2C1=O)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Abitrexate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Abitrexate-Methotrexate-chemical-structure-S1210.gif |