Methotrexate
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
| Trivial name | NCI-C04671, Amethopterin, CL14377, WR19039 |
| Catalog Number | S1210 |
| Molecular Formula | C14H9Cl3 |
| CAS# | 59-05-2 |
| Inchi | InChI=1S/C14H9Cl3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9H/b2-1+ |
| Inchi Key | JMYNPQVCVQVODQ-OWOJBTEDSA-N |
| SMILES | C1=CC(=CC=C1C=CC2=CC(=CC(=C2)Cl)Cl)Cl |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Abitrexate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Abitrexate-Methotrexate-chemical-structure-S1210.gif |