KU-55933
KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. KU‑55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy‑initiating kinase ULK1 and results in a significant decrease of autophagy.
| Trivial name | ATM Kinase Inhibitor |
| Catalog Number | S1092 |
| Molecular Formula | C6H8O6 |
| CAS# | 587871-26-9 |
| Inchi | InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) |
| Inchi Key | KQTIIICEAUMSDG-UHFFFAOYSA-N |
| SMILES | C(C(CC(=O)O)C(=O)O)C(=O)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/KU-55933.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KU-55933-chemical-structure-S1092.gif |