ZM 39923 hydrochloride
ZM 39923 hydrochloride is a potent and selective inhibitor of Janus tyrosine kinase 3 (JAK3) (pIC50 = 7.1, 5.6, 4.4, and < 5.0 for JAK3, EGFR, JAK1 and CDK4, respectively). ZM 39923 breaks down in neutral buffer (t½ = 36 mins, pH 7.43, 25°C) to produce an active analog, ZM 449829.
| Catalog Number | 58753-54-1 |
| Alternative Name(s) | ZM 39923; ZM-39923; ZM39923 HCl; 3-benzylisopropylamino-1-naphthalen-2-yl-propan-1-one hydrochloride; JAK3 Inhibitor IV |
| Molecular Formula | C15H19N5O·C3H4O4 |
| CAS# | 58753-54-1 |
| Purity | ≥99% |
| Inchi | InChI=1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H |
| Inchi Key | NJTUORMLOPXPBY-UHFFFAOYSA-N |
| Size | Please inquire |
| Supplier Page | https://www.bocsci.com/zm-39923-hydrochloride-cas-58753-54-1-item-77799.html |