L-Alanosine
L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency.
| Trivial name | NSC-153353, SDX-102 |
| Catalog Number | E7774 |
| Molecular Formula | C24H28N2O3 |
| CAS# | 5854-93-3 |
| Inchi | InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3 |
| Inchi Key | HRRBJVNMSRJFHQ-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/l-alanosine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7774-l-alanosine-chemical-structure-tube.png |