Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC50 of 0.7 nM.In Vitro: Olvanil affects C6 glioma cell proliferation (IC50?value of 5.5 μM)[2]In Vivo: Olvanil is one capsaicin analog, which acts as an agonist at the vanilloid receptor.?Olvanil may have causes an anxiogenic-like effect.?Doses of 0, 0.2, 1.0 and 5.0 mg/kg Olvanil, respectively, yielded percent open arm entries at 5 min of 25±10.1, 19.3±7.1, 14.9±5.9 and 0±0.