Ridaforolimus (Deforolimus, MK-8669)

Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.

Price Not Available 5mg Ridaforolimus (Deforolimus, MK-8669) Supplier Page

Trivial name	AP23573
Catalog Number	S1022
Molecular Formula	C22H26N2O9
CAS#	572924-54-0
Inchi	InChI=1S/C22H24N2O8.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H2/t7-,10+,14+,15-,17-,22-;/m 0./s1
Inchi Key	XQTWDDCIUJNLTR-CVHRZJFOSA-N
SMILES	CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/Deforolimus.html
Additional Information	https://file.selleck.cn/downloads/struct/Deforolimus-Ridaforolimus-chemical-structure-S1022.gif