Ridaforolimus (Deforolimus, MK-8669)
Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.
| Trivial name | AP23573 |
| Catalog Number | S1022 |
| Molecular Formula | C7H12O3 |
| CAS# | 572924-54-0 |
| Inchi | InChI=1S/C7H12O3/c8-6-3-1-5(2-4-6)7(9)10/h5-6,8H,1-4H2,(H,9,10)/t5-,6- |
| Inchi Key | HCFRWBBJISAZNK-IZLXSQMJSA-N |
| SMILES | C1CC(CCC1C(=O)O)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Deforolimus.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Deforolimus-Ridaforolimus-chemical-structure-S1022.gif |