Avatrombopag hydrochloride

Avatrombopag hydrochloride(AKR-501 hydrochloride, YM477 hydrochloride) is an orally administered second generation agonist of Thrombopoietin receptor(TpoR) with an EC50 value of 3.3 nM. It is used in the treatment of primary chronic immune thrombocytopenia (ITP).

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Trivial name	AKR-501 hydrochloride, YM477 hydrochloride
Catalog Number	E4969
Molecular Formula	C20H22N8O5
CAS#	570403-17-7
Inchi	InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
Inchi Key	FBOZXECLQNJBKD-ZDUSSCGKSA-N
SMILES	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/avatrombopag-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E4969-Avatrombopag-hydrochloride-chemical-structure.png