NSC87877
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
| Trivial name | N/A |
| Catalog Number | S8182 |
| Molecular Formula | C19H13N3O7S2.2Na |
| CAS# | 56932-43-5 |
| Inchi | InChI=1S/C19H13N3O7S2.2Na/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13;;/h1-10,23H,(H,24,25,26)(H,27,28,29);;/q;2*+1/p-2/b22-21+;; |
| Inchi Key | IFVGQKHFUZRWNA-ZPZFBZIMSA-L |
| SMILES | C1=CC2=C(C=C(C(=C2N=C1)O)N=NC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+] |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/nsc87877.html |
| Additional Information | https://file.selleck.cn/downloads/struct/nsc87877-chemical-structure-s8182.gif |