Halofuginone
Halofuginone (RU-19110) is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.
| Trivial name | RU-19110 |
| Catalog Number | S8144 |
| Molecular Formula | C16H17BrClN3O3 |
| CAS# | 55837-20-2 |
| Inchi | InChI=1S/C16H17BrClN3O3/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14/h5-6,8,14-15,19,23H,1-4,7H2/t14-,15+/m1/s1 |
| Inchi Key | LVASCWIMLIKXLA-CABCVRRESA-N |
| SMILES | C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/halofuginone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/halofuginone-chemical-structure-s8144.gif |