Deferasirox (Fe3+ chelate)
Deferasirox (Fe3+ chelate) (Exjade) is an oral tridentate iron chelator used for reducing transfusional chronic iron overload. It exhibits efficacy in iron-overloaded patients with anemias, thalassemia, sickle cell disease and myelodysplastic syndromes. It is also an orally effective antitumor agent against solid tumors.
| Trivial name | Exjade |
| Catalog Number | E6006 |
| Molecular Formula | C45H74O11 |
| CAS# | 554435-83-5 |
| Inchi | InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18 ,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13-,17-15-,21-18+/t25-,26-,27+,28+,29?,30-,31-,32-,33-,34-,35-,36-,38+,40+,41+,42-,44+,45-/m0/s1 |
| Inchi Key | MNULEGDCPYONBU-WFTQPAASSA-N |
| SMILES | CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/deferasirox-fe3-chelate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E6006-Deferasirox-Fe3-chelate-chemical-structure.png |