Beclomethasone 17-propionate
Beclomethasone 17-propionate (Beclomethasone-17-monopropionate), an active metabolite of Beclomethasone dipropionate (HY-13571), is a glucocorticoid receptor (GR) agonist. Beclomethasone 17-propionate exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone 17-propionate effectively suppresses cytokine production in chronic obstructive pulmonary disease (COPD) lung macrophages.
Trivial name | Beclomethasone-17-monopropionate, 17-BMP |
Catalog Number | E7912 |
Molecular Formula | C26H20F3N7O |
CAS# | 5534-18-9 |
Inchi | InChI=1S/C26H20F3N7O/c1-15-8-9-16(25(37)32-19-7-3-6-18(12-19)26(27,28)29)11-21(15)33-23-20-14-31-36(2)24(20)35-22(34-23)17-5-4-10-30-13-17/h3-14H,1-2H3,(H,32,37)(H,33,34,35) |
Inchi Key | ZCCPLJOKGAACRT-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=C4C=NN(C4=NC(=N3)C5=CN=CC=C5)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/beclomethasone-17-propionate.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7912-beclomethasone-17-propionate-chemical-structure-tube.png |