Busulfan
Busulfan is a cell cycle non-specific alkylating antineoplastic agent. It causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase activity. It also induces apoptosis. It is an immunosuppressive and myeloablative chemotherapeutic agent.Busulfan (NSC-750) can be used to induce animal models of Anemia.
Trivial name | NSC-750 |
Catalog Number | S1692 |
Molecular Formula | C26H24ClN3O3.HCl |
CAS# | 55-98-1 |
Inchi | InChI=1S/C26H24ClN3O3.ClH/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31;/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31);1H/b22-16+; |
Inchi Key | YYIMMVXTWBIEAG-YHLMHSEJSA-N |
SMILES | CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)C=C4C5=C(C=CC(=C5)Cl)NC4=O.Cl |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Busulfan(Busulfex).html |
Additional Information | https://file.selleck.cn/downloads/struct/Busulfan-Myleran-Busulfex-chemical-structure-S1692.gif |