α-Conotoxin GID | MedChemExpress (MCE)
α-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (α7), 3 nM (α3β2)， 150 nM (α4β2), respectively. α-Conotoxin GID is small disulfide-rich peptide, with potential to inhibit chronic pain. α-Conotoxin GID contains a C-terminal carboxylate, thus substitution with a C-terminal carboxamide results in loss of α4β2 nAChR. α-Conotoxin GID can be isolated from the Conus species[1][2][3].
| Trivial name | α-Conotoxin GID |
| Catalog Number | HY-P5147 |
| Research Area | Neurological Disease |
| CAS# | 547741-78-6 |
| Purity | ≥98.00% |
| SMILES | O=C1[C@@]2([H])N(C[C@@H](C2)O)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]3([H])NC([C@@H](NC([C@@]4([H])N(CCC4)C([C@@H](NC([C@@H](NC([C@](NC([C@H](CSSC3)NC([C@H](CC(C(O)=O)C(O)=O)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O)=O)([H])CSSC[C@H](NC([C@@H](NC([C@@H](N1)CC5=CN=CN5)=O)C(C)C)=O)C(O)=O)=O)CO)=O)CC(N)=O)=O)=O)C)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(N)=O)=O)CC(N)=O)=O |
| PubChem Chemical Structure ID | 168432163 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/α-conotoxin-gid.html |