R(+)-Methylindazone
R(+)-Methylindazone (R(+)-IAA-94) is a potentand specific indanyloxyacetic inhibitor of the renal epithelial chloride channel and exacerbates myocardial infarction by impairing mitochondrial calcium retention capacity (CRC), leading to mitochondrial permeability transition pore (mPTP) opening and increased cell death during ischemia-reperfusion injury.
Trivial name | R(+)-IAA-94 |
Catalog Number | E7830 |
Molecular Formula | C14H14ClFN8 |
CAS# | 54197-31-8 |
Inchi | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1 |
Inchi Key | PDOQBOJDRPLBQU-QMMMGPOBSA-N |
SMILES | CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/r-methylindazone.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7830-R-Methylindazone-chemical-structure.png |