Palosuran
Palosuran (ACT-058362) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran can improves pancreatic and renal function in diabetic rats.
| Trivial name | ACT-058362 |
| Catalog Number | E7522 |
| Molecular Formula | C14H12ClNO2 |
| CAS# | 540769-28-6 |
| Inchi | InChI=1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18) |
| Inchi Key | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/palosuran.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7522-palosuran-chemical-structure-tube.png |