3,4-Diaminopyridine

3,4-Diaminopyridine (Amifampridine, pyridine-3,4-diamine) blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations. It is a drug predominantly used in the treatment of a number of rare muscle diseases.

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Trivial name Amifampridine, pyridine-3,4-diamine
Catalog Number S4622
Molecular Formula C30H35N7O2
CAS# 54-96-6
Inchi InChI=1S/C30H35N7O2/c1-6-29(38)32-24-17-25(28(39-5)18-27(24)36(4)16-15-35(2)3)34-30-31-14-13-23(33-30)22-19-37(20-11-12-20)26-10-8-7-9-21(22)26/h6-10,13-14,17-20H,1,11-12,15-16H2,2-5H3,(H,32,38)(H,31, 33,34)
Inchi Key DOEOECWDNSEFDN-UHFFFAOYSA-N
SMILES CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OC
Size 1g
Supplier Page http://www.selleckchem.com/products/3-4-diaminopyridine.html
Additional Information https://file.selleck.cn/downloads/struct/3-4-diaminopyridine-chemical-structure-s4622.gif