CP-724714
CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
| Trivial name | N/A |
| Catalog Number | S1167 |
| Molecular Formula | C27H27N5O3 |
| CAS# | 537705-08-1 |
| Inchi | InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+ |
| Inchi Key | LLVZBTWPGQVVLW-SNAWJCMRSA-N |
| SMILES | CCOC(=O)NCC=CC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OC4=CN=C(C=C4)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/CP-724714.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CP-724714-chemical-structure-S1167.gif |