Mefloquine
Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
| Trivial name | Lariam, WR-142490 |
| Catalog Number | E4872 |
| Molecular Formula | C25H23N7OS.HCl |
| CAS# | 53230-10-7 |
| Inchi | InChI=1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H |
| Inchi Key | DTGRRMPPXCRRIM-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/mefloquine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4872-Mefloquine-chemical-structure.png |