Mefloquine
Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
| Trivial name | Lariam, WR-142490 |
| Catalog Number | E4872 |
| Molecular Formula | C20H19BrN4O3 |
| CAS# | 53230-10-7 |
| Inchi | InChI=1S/C20H19N4O3.BrH/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;/h3-8,11H,9-10,12H2,1-2H3;1H/q+1;/p-1 |
| Inchi Key | QBIYUDDJPRGKNJ-UHFFFAOYSA-M |
| SMILES | CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-] |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/mefloquine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4872-Mefloquine-chemical-structure.png |