Pirfenidone
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.
| Trivial name | S-7701, AMR-69 |
| Catalog Number | S2907 |
| Molecular Formula | C21H21BrN4O5 |
| CAS# | 53179-13-8 |
| Inchi | InChI=1S/C21H21BrN4O5/c1-23-19(27)13-7-5-6-8-15(13)31-20-14(22)11-24-21(26-20)25-12-9-16(28-2)18(30-4)17(10-12)29-3/h5-11H,1-4H3,(H,23,27)(H,24,25,26) |
| Inchi Key | NEXGBSJERNQRSV-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/pirfenidone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Pirfenidone-chemical-structure-s2907.jpg |