Puromycin
Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3′ end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research.
| Trivial name | CL13900, Puromycine |
| Catalog Number | E4996 |
| Molecular Formula | C21H20ClNO5 |
| CAS# | 53-79-2 |
| Inchi | InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1 |
| Inchi Key | BIIVYFLTOXDAOV-YVEFUNNKSA-N |
| SMILES | CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/puromycin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4996-Puromycin-chemical-structure.png |