SIS3 HCl
SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways.
| Trivial name | N/A |
| Catalog Number | S7959 |
| Molecular Formula | C28H27N3O3.HCl |
| CAS# | 521984-48-5 |
| Inchi | InChI=1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,18H2,1-3H3;1H/b12-11+; |
| Inchi Key | CDKIEBFIMCSCBB-CALJPSDSSA-N |
| SMILES | CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sis3-hcl.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sis3-chemical-structure-s7959.gif |