Raltegravir

Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.

Price Not Available 5mg Raltegravir Supplier Page
Trivial name MK-0518
Catalog Number S2005
Molecular Formula C20H21FN6O5
CAS# 518048-05-0
Inchi InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
Inchi Key CZFFBEXEKNGXKS-UHFFFAOYSA-N
SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F
Size 5mg
Supplier Page http://www.selleckchem.com/products/Raltegravir-(MK-0518).html
Additional Information https://file.selleck.cn/downloads/struct/Raltegravir-MK-0518-chemical-structure-S2005.gif