3-MA (3-Methyladenine)
3-MA (3-Methyladenine) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. Solutions are unstable and should be fresh-prepared.
| Trivial name | NSC 66389 |
| Catalog Number | S2767 |
| Molecular Formula | C19H21N3O3S |
| CAS# | 5142-23-4 |
| Inchi | InChI=1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10- |
| Inchi Key | LOGJQOUIVKBFGH-YBEGLDIGSA-N |
| SMILES | CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=O)C2=CC3=CC4=C(N3)CCCC4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/3-methyladenine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/3-Methyladenine-chemical-structure-s2767.gif |
