3-MA (3-Methyladenine)
3-MA (3-Methyladenine) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. Solutions are unstable and should be fresh-prepared.
Trivial name | NSC 66389 |
Catalog Number | S2767 |
Molecular Formula | C6H7N5 |
CAS# | 5142-23-4 |
Inchi | InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3 |
Inchi Key | FSASIHFSFGAIJM-UHFFFAOYSA-N |
SMILES | CN1C=NC(=N)C2=C1N=CN2 |
Size | 2g |
Supplier Page | http://www.selleckchem.com/products/3-methyladenine.html |
Additional Information | https://file.selleck.cn/downloads/struct/3-Methyladenine-chemical-structure-s2767.gif |