Mizoribine
Mizoribine is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5′-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.
| Trivial name | NSC 289637,HE 69 |
| Catalog Number | S1384 |
| Molecular Formula | C22H23F3N8O |
| CAS# | 50924-49-7 |
| Inchi | InChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34) |
| Inchi Key | XXJXHXJWQSCNPX-UHFFFAOYSA-N |
| SMILES | CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Mizoribine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Mizoribine-Bredinin-chemical-structure-S1384.gif |