GW441756
GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
| Trivial name | N/A |
| Catalog Number | S2891 |
| Molecular Formula | C17H13N3O |
| CAS# | 504433-23-2 |
| Inchi | InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21) |
| Inchi Key | NXNQLECPAXXYTR-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gw-441756.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2891-gw441756-chemical-structure.png |