NSC 74859 (S3I-201)
NSC 74859 (S3I-201) shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.
Catalog Number | S1155 |
Molecular Formula | C18H22N2O2 |
CAS# | 501919-59-1 |
Inchi | InChI=1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3 |
Inchi Key | BQXQGZPYHWWCEB-UHFFFAOYSA-N |
SMILES | CC(C)NCC(COC1=CC=CC2=C1C3=CC=CC=C3N2)O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/S31-201.html |
Additional Information | https://file.selleck.cn/downloads/struct/NSC-74859-S3I-201-chemical-structure-S1155.gif |