NSC 74859 (S3I-201)
NSC 74859 (S3I-201) shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5.
| Catalog Number | S1155 |
| Molecular Formula | C16H15NO7S |
| CAS# | 501919-59-1 |
| Inchi | InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21) |
| Inchi Key | HWNUSGNZBAISFM-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/S31-201.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NSC-74859-S3I-201-chemical-structure-S1155.gif |