2-APQC
2-APQC is a potent activator of SIRT3 with a Kd value of 2.756 μM. It alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis, exhibiting promising cardioprotective potential in vitro and in vivo. It may serve as a potential candidate for future heart failure (HF) therapeutics.
| Catalog Number | E5907 |
| Molecular Formula | C14H12O3 |
| CAS# | 500271-63-6 |
| Inchi | InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ |
| Inchi Key | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
| SMILES | C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/2-apqc.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5907-2-APQC-chemical-structure.png |