Proguanil
Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
| Trivial name | chlorguanide, chloroguanide |
| Catalog Number | S5927 |
| Molecular Formula | C11H16ClN5 |
| CAS# | 500-92-5 |
| Inchi | InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17) |
| Inchi Key | SSOLNOMRVKKSON-UHFFFAOYSA-N |
| SMILES | CC(C)N=C(N)N=C(N)NC1=CC=C(C=C1)Cl |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/proguanil.html |
| Additional Information | https://file.selleck.cn/downloads/struct/proguanil-chemical-structure-s5927.gif |