G-418
G-418 (Geneticin, Antibiotic G-418) is an aminoglycoside antibiotic originally isolated from Micromonospora rhodorangea. It functions by binding to the ribosomal subunit, thereby inhibiting translational elongation and disrupting protein synthesis in both prokaryotic and eukaryotic cells, thus impairing cell growth and viability.
| Trivial name | Geneticin, Antibiotic G-418 |
| Catalog Number | E7524 |
| Molecular Formula | C12H14N4O4S |
| CAS# | 49863-47-0 |
| Inchi | InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) |
| Inchi Key | ZZORFUFYDOWNEF-UHFFFAOYSA-N |
| SMILES | COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/g-418.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7524-G-418-chemical-structure.png |