Selisistat (EX 527)
Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.
| Trivial name | SEN0014196 |
| Catalog Number | S1541 |
| Molecular Formula | C13H13ClN2O |
| CAS# | 49843-98-3 |
| Inchi | InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17) |
| Inchi Key | FUZYTVDVLBBXDL-UHFFFAOYSA-N |
| SMILES | C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/EX-527.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ex-527-selisistat-chemical-structure-s1541.gif |