AEE788 (NVP-AEE788)

AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCĪ± and CDK1. Phase 1/2.

Price Not Available 5mg AEE788 (NVP-AEE788) Supplier Page
Trivial name N/A
Catalog Number S1486
Molecular Formula C27H32N6
CAS# 497839-62-0
Inchi InChI=1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2H3,(H2,28,29,30,31)/t20-/m1/s1
Inchi Key OONFNUWBHFSNBT-HXUWFJFHSA-N
SMILES CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
Size 5mg
Supplier Page http://www.selleckchem.com/products/AEE788.html
Additional Information https://file.selleck.cn/downloads/struct/AEE-788-chemical-structure-S1486.gif