Elesclomol (STA-4783)
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.Elesclomol (STA-4783) is a potent copper ionophore and can be used in the research of copper-dependent cell death (cuproptosis).
Trivial name | N/A |
Catalog Number | S1052 |
Molecular Formula | C19H20N4O2S2 |
CAS# | 488832-69-5 |
Inchi | InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25) |
Inchi Key | BKJIXTWSNXCKJH-UHFFFAOYSA-N |
SMILES | CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2 |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/Elesclomol.html |
Additional Information | https://file.selleck.cn/downloads/struct/Elesclomol-chemical-structure-S1052.gif |