(+)-Bicuculline
(+)-Bicuculline (d-Bicuculline) is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.
| Trivial name | d-Bicuculline |
| Catalog Number | S7071 |
| Molecular Formula | C20H17NO6 |
| CAS# | 485-49-4 |
| Inchi | InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 |
| Inchi Key | IYGYMKDQCDOMRE-ZWKOTPCHSA-N |
| SMILES | CN1CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/bicuculline.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Bicuculline-chemical-structure-s7071.gif |